Dysplastic nevus - Nevus Dysplastîk
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Dysplastic nevi - Biopsî ji bo Rojavayiyan tê pêşniyar kirin.
References
Dysplastic nevus , ku wekî nevusek atypical an Clarks jî tê zanîn, di dermatolojî û dermatopatholojiyê de nîqaşan derxistiye holê. Bijîjk bi gelemperî van molan biyopsî dikin ji ber ku ew dikarin anormal xuya bikin û fikarên li ser melanoma zêde bikin.
A dysplastic nevus is also referred to as an atypical or Clarks nevus and has been the topic of much debate in the fields of dermatology and dermatopathology. It is an acquired mole demonstrating a unique clinical and histopathologic appearance that sets it apart from the common nevus. These moles appear atypical clinically, often with a fried-egg appearance, and are commonly biopsied by providers due to the concern for melanoma.
A dysplastic nevus is also referred to as an atypical or Clarks nevus and has been the topic of much debate in the fields of dermatology and dermatopathology. It is an acquired mole demonstrating a unique clinical and histopathologic appearance that sets it apart from the common nevus. These moles appear atypical clinically, often with a fried-egg appearance, and are commonly biopsied by providers due to the concern for melanoma.
Dysplastic nevi , ku wekî nevi atypical an Clark jî tê zanîn, carinan dikare bibe sedema melanoma. Nêzîkî 36% ji melanomas nêzîkî neviyên dysplastîk têne dîtin. Nîşaneyên ku dibe ku nevusek dîsplastîk veguhere melanomayê, şeklê nehevseng, bêtir guhertinên pigmentê, an rengek gewr e. Ev penceşêr bi gelemperî di temenek piçûk de çêdibin (dora nîvê salên sî) , dikarin pirjimar bin, û bi gelemperî li ser stûnê ne. Ji hêla genetîkî ve, dysplastic nevi di navbera nevi û melanoma de ne. Lêbelê, tenê %20 heta %30ê melanomayan ji neviyên heyî tên. Ji ber ku piraniya nevî nabin melanoma, bi gelemperî nayê pêşniyar kirin ku ew bi pêşgiriyê werin rakirin.
Dysplastic nevus, also called atypical or Clark nevus, can be precursor to melanoma, as the observation that 36% of melanomas have dysplastic nevi near the invasive tumor supports. Signs that a dysplastic nevus may have transitioned into a melanoma include asymmetry in contour, a noticeable increase in pigment variations, or a grayish tint indicating regression. These malignancies typically arise at a younger age (mid-thirties), are sometimes multiple, and are often found on the trunk. Molecularly, dysplastic nevi have a profile intermediate between benign nevi and malignant melanoma. While there is a recognized connection between dysplastic nevi and melanoma, it’s crucial to note that only about 20% to 30% of melanomas evolve from preexisting nevi. Given that the majority of dysplastic and typical nevi do not develop into melanoma, preventive removal of melanocytic nevi is not typically advised.
Dysplastic nevus, also called atypical or Clark nevus, can be precursor to melanoma, as the observation that 36% of melanomas have dysplastic nevi near the invasive tumor supports. Signs that a dysplastic nevus may have transitioned into a melanoma include asymmetry in contour, a noticeable increase in pigment variations, or a grayish tint indicating regression. These malignancies typically arise at a younger age (mid-thirties), are sometimes multiple, and are often found on the trunk. Molecularly, dysplastic nevi have a profile intermediate between benign nevi and malignant melanoma. While there is a recognized connection between dysplastic nevi and melanoma, it’s crucial to note that only about 20% to 30% of melanomas evolve from preexisting nevi. Given that the majority of dysplastic and typical nevi do not develop into melanoma, preventive removal of melanocytic nevi is not typically advised.
Melanoma celebek tumor e ku dema ku melanocît, hucreyên ku ji rengê çerm berpirsiyar in, dibin kanserê çêdibe. Melanocytes ji qerta nervê çêdibin. Ev tê vê wateyê ku melanomas ne tenê li ser çerm, lê di heman demê de li deverên din ên ku hucreyên qirika neuralî lê koç dikin, mîna rêça gastrointestinal û mêjî jî dikarin pêşve bibin. Rêjeya zindîbûnê ji bo nexweşên bi melanoma qonaxên destpêkê (qonaxa 0) 97% bilind e, di heman demê de ji bo kesên ku bi nexweşiya qonaxa pêşkeftî (qonaxa IV) hatine teşhîs kirin, bi girîngî dadikeve nêzî %10.
A melanoma is a tumor produced by the malignant transformation of melanocytes. Melanocytes are derived from the neural crest; consequently, melanomas, although they usually occur on the skin, can arise in other locations where neural crest cells migrate, such as the gastrointestinal tract and brain. The five-year relative survival rate for patients with stage 0 melanoma is 97%, compared with about 10% for those with stage IV disease.
A melanoma is a tumor produced by the malignant transformation of melanocytes. Melanocytes are derived from the neural crest; consequently, melanomas, although they usually occur on the skin, can arise in other locations where neural crest cells migrate, such as the gastrointestinal tract and brain. The five-year relative survival rate for patients with stage 0 melanoma is 97%, compared with about 10% for those with stage IV disease.
○ Rîska penceşêrê
Wekî ku di mirovên Kafkasyayî yên Dewletên Yekbûyî de tê dîtin, kesên ku bi neviyên dysplastîk re xetera melanoma ji% 10 mezintir e di jiyanê de heye. Ji hêla din ve, yên ku bê nevusên dîsplastîk ne xwedî metirsiya pêşkeftina melanoma ji %1 kêmtir in.
○ Pêşdarî ji bo kesên bi nevi bi dysplastîk
Xwe-muayenekirina çerm bi gelemperî ji bo pêşîlêgirtina melanoma (bi destnîşankirina neviyên atîpîkî yên ku dikarin werin rakirin) an jî ji bo tespîtkirina zû ya tumorên heyî tê pêşniyar kirin. Kesên ku xwedan dîrokek kesane an malbatî ya penceşêra çerm an pir neviyên atipîkî ne, divê bi kêmanî salê carekê biçin dermatologek da ku pê ewle bin ku ew bi melanoma pêş nekevin.
Kurtenivîsa [ABCDE] ji bo alîkariya pêşkêşkerên lênihêrîna tenduristî û kesên laşî ku taybetmendiyên sereke yên melanoma bi bîr bînin bikêr bûye. Mixabin ji bo mirovê navîn, gelek keratozên seborrheîk, hin lentigo senilis, û tewra şûjin jî dibe ku xwedî taybetmendiyên [ABCDE] bin, û nekarin ji melanomayê bêne cûda kirin.
○ [ABCDE]
Asymmetrical: Birîna çerm a asimetrîk.
Border: Sînorê birînê ne asayî ye.
Color: Melanoma bi gelemperî gelek rengên nerêkûpêk hene.
Diameter: neviyên ku ji 6 mm mezintir in ji neviyên piçûk zêdetir melanoma dibin.
Evolution: Pêşveçûn (ango guherîn) nevus an birînek dikare nîşan bide ku birîn xirab dibe.